肝素钠不良反应
The adverse reaction of heparin sodium
1.最常见出血，可能发生任何部位。
The 1. most common bleeding may occur in any part.
2.常见寒战、发热、荨麻疹等过敏反应。
2. common chills, fever, urticaria and other allergic reactions.
3.长期用药可致脱发和短暂的可逆性秃头症、骨质疏松和自发性骨折。
3. long-term use can cause hair loss and transient reversible alopecia, osteoporosis and spontaneous fracture.
4.注射局部可见局部刺激、红斑、轻微头痛、血肿、溃疡等。肌内注射后更严重，因此不宜肌内注射。
4. local injection of visible local irritation, erythema, mild headache, hematoma, ulcer etc.. More serious after intramuscular injection, intramuscular injection should not be so.
5.尚见短暂的血小板减少症。肝素诱发的血小板数减少（HIT）是由于肝素-血小板4因子抗体复合物结合于血小板4因子受体所致。可激活血小板聚集，造成小动脉栓塞。虽少见，但可致死。如出现HIT应立即停用肝素。
5. see is transient thrombocytopenia. Heparin induced platelet count reduction (HIT) is due to heparin platelet factor 4 antibody complexes binding to platelets induced by 4 factor receptor. Activation of platelet aggregation, resulting in small artery embolism. Although it is rare, but can be deadly. If the HIT should immediately stop using heparin.